Comprehensive analysis of telomere maintenance from transcriptomic, epigenetic, and loss-of-function profiles of cancer cell lines elucidates features of telomere regulation in cancer.
Stephen R Piccolo, Zachary E Ence ... Andrea H Bild
Descriptions, examples, and tools to enable biologists to use the Common Workflow Language for data processing and to facilitate computational reproducibility.
With a data-driven mathematical modelling approach, within-host ecological information alone can provide clues on the mechanistic basis of diverse malaria infection outcomes.
Simple mathematical reasoning shows that the large amount of synaptic turnover seen in many parts of the brain is in fact optimal for memory retention.
Ryan Z Friedman, David M Granas ... Michael A White
Silencers and enhancers targeted by a common transcription factor in photoreceptors are distinguished by the number and diversity of binding transcription factor binding sites they contain.
Christopher P Mancuso, Hyunseok Lee ... Ahmad S Khalil
Laboratory experiments using a microbial community and mathematical modeling reveal how environmental disturbances can predictably alter the diversity and composition of an ecosystem.
Funding inequalities for NIH-supported research project grant investigators and organizations have increased over the past 25 years, but have modestly decreased over the past 3 years.
PARROT makes it easy for anyone to train and use system- or data-specific deep learning models that map between protein sequence and arbitrary sequence annotations.
Hannah R Meredith, John R Giles ... Amy Wesolowski
Mobile phone data reveal aspects of human mobility patterns in Sub-Saharan Africa missed by standard spatial models however, model estimates can be improved by accounting for trip urbanicity and region.
